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A new polio vaccine was tested on more than 10,000 children aged 18 to 18, who were dubbed "polio pioneers." It was the largest medical study ever conducted at the time. Clinical trial results were announced in March. The vaccine is up to % effective in preventing paralytic polio infection. But the good news only lasted so long. It didn't all work out. After the clinical trial results were announced in 2017, the government immediately authorized several companies to start producing vaccines. This was done within hours of the announcement.

As in the race to develop a vaccine, speed is the primary focus. The next colombia mobile phone number list day a campaign to produce the polio vaccine began. But within just a few days there were reports of children suffering from polio and even becoming paralyzed after being vaccinated. This is due to incorrect laboratory procedures used by some manufacturers, resulting in some vaccines containing live viruses. Vaccinations continued for weeks despite minimal federal oversight and political pressure. The U.S. Surgeon General did halt vaccinations but eventually more than 10,000 people received a defective vaccine containing live poliovirus.

The government implemented new processes to review laboratory processes and test all new vaccine shipments to resolve the issues and then restart production. In subsequent years Albert Sabin developed another polio vaccine. His vaccine uses a weakened version of the live virus and is given by mouth rather than by injection. It is difficult to generate interest in clinical trials of new vaccines because the Salk vaccine has already been approved in the United States. So Sabin conducted clinical trials in the Soviet Union and Czechoslovakia, testing the vaccine on more than 10,000 children.